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Recombinant human MED27 protein

CAT: 0112-ATGP2650-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2650-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MED27 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e. g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Recombinant human MED27 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Mediator complex subunit 27, CRAP34, CRSP34, CRSP8, TRAP37
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
37.8 kDa (334aa)
Additionnal Information
MED27, Mediator complex subunit 27, CRAP34, CRSP34, CRSP8, TRAP37, ATGP2650-10 µg, ATGP2650-20 µg, ATGP2650-50 µg, ATGP2650-100 µg, ATGP2650-250 µg, ATGP2650-500 µg, ATGP2650-1 mg, ATGP2650-10, ATGP2650-20, ATGP2650-50, ATGP2650-100, ATGP2650-250, ATGP2650-500, ATGP2650-1
References & Citations
Malik S., et al. (2000) Mol. Cell. 5:753-760; ; Ryu S., et al. (1999) Nature. 397:446-450;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_004260.2
Uniprot Accession Number
Q6P2C8
Species
Human
AA Sequence
MADVINV SVNLEAFSQA ISAIQALRSS VSRVFDCLKD GMRNKETLEG REKAFIAHFQ DNLHSVNRDL NELERLSNLV GKPSENHPLH NSGLLSLDPV QDKTPLYSQL LQAYKWSNKL QYHAGLASGL LNQQSLKRSA NQMGVSAKRR PKAQPTTLVL PPQYVDDVIS RIDRMFPEMS IHLSRPNGTS AMLLVTLGKV LKVIVVMRSL FIDRTIVKGY NENVYTEDGK LDIWSKSNYQ VFQKVTDHAT TALLHYQLPQ MPDVVVRSFM TWLRSYIKLF QAPCQRCGKF LQDGLPPTWR DFRTLEAFHD TCRQ

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