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Recombinant human CD5 protein

CAT: 0112-ATGP2639-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2639-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukemia, while relatively rare, is associated with a poor prognosis. Recombinant human CD5 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
T-cell surface glycoprotein CD5, LEu1, T1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
41.0 kDa (371aa)
Additionnal Information
CD5, T-cell surface glycoprotein CD5, LEu1, T1, ATGP2639-10 µg, ATGP2639-20 µg, ATGP2639-50 µg, ATGP2639-100 µg, ATGP2639-250 µg, ATGP2639-500 µg, ATGP2639-1 mg, ATGP2639-10, ATGP2639-20, ATGP2639-50, ATGP2639-100, ATGP2639-250, ATGP2639-500, ATGP2639-1
References & Citations
Berland R. et al. (2002) Annu. Rev. Immunol. 20:253-300.; ; Osman N. et al. (1992) Eur. J. Immunol. 22:2995-3000.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Immunology
NCBI Accession Number
NP_055022
Uniprot Accession Number
P06127
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSRLSWYDP DFQARLTRSN SKCQGQLEVY LKDGWHMVCS QSWGRSSKQW EDPSQASKVC QRLNCGVPLS LGPFLVTYTP QSSIICYGQL GSFSNCSHSR NDMCHSLGLT CLEPQKTTPP TTRPPPTTTP EPTAPPRLQL VAQSGGQHCA GVVEFYSGSL GGTISYEAQD KTQDLENFLC NNLQCGSFLK HLPETEAGRA QDPGEPREHQ PLPIQWKIQN SSCTSLEHCF RKIKPQKSGR VLALLCSGFQ PKVQSRLVGG SSICEGTVEV RQGAQWAALC DSSSARSSLR WEEVCREQQC GSVNSYRVLD AGDPTSRGLF CPHQKLSQCH ELWERNSYCK KVFVTCQDPN P

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