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Recombinant human EPCR protein

CAT: 0112-ATGP2638-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2638-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. This protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. Recombinant human PROCR protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Protein C receptor endothelial, Protein C receptor, endothelial, CCCA, CCD41, CD201, EPCR
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
24.4 kDa (216aa)
Additionnal Information
EPCR, Protein C receptor endothelial, Protein C receptor, endothelial, CCCA, CCD41, CD201, EPCR, ATGP2638-10 µg, ATGP2638-20 µg, ATGP2638-50 µg, ATGP2638-100 µg, ATGP2638-250 µg, ATGP2638-500 µg, ATGP2638-1 mg, ATGP2638-10, ATGP2638-20, ATGP2638-50, ATGP2638-100, ATGP2638-250, ATGP2638-500, ATGP2638-1
References & Citations
Fukudome K. et al. (1994) J Biol Chem. 269:26486-26491.; ; Van de Wouwer M. et al. (2005) Arterioscler. Thromb. Vasc. Biol. 24:1374-83.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Cardiovascular
NCBI Accession Number
NP_006395
Uniprot Accession Number
Q9UNN8
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSSQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTS

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