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Recombinant human EMP/MAEA protein

CAT: 0112-ATGP2251-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2251-250Size:250 µg
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Description
Macrophage erythroblast attacher isoform 1, also known as MAEA, is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, MAEA contains one CTLH domain and one LisH domain. MAEA can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, MAEA is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Recombinant human MAEA protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Macrophage erythroblast attacher isoform 1, EMLP, EMP, GID9, HLC-10, PIG5
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
47.7 kDa (419aa)
Additionnal Information
EMP, MAEA, Macrophage erythroblast attacher isoform 1, EMLP, EMP, GID9, HLC-10, PIG5, ATGP2251-10 µg, ATGP2251-20 µg, ATGP2251-50 µg, ATGP2251-100 µg, ATGP2251-250 µg, ATGP2251-500 µg, ATGP2251-1 mg, ATGP2251-10, ATGP2251-20, ATGP2251-50, ATGP2251-100, ATGP2251-250, ATGP2251-500, ATGP2251-1
References & Citations
Soni S., et al. (2006) J Biol Chem. 281:20181-20189.; ; Bala S., et al. (2006) Biochem Biophys Res Commun. 342:1040-1048.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001017405
Uniprot Accession Number
Q7L5Y9
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAVQESA AQLSMTLKVQ EYPTLKVPYE TLNKRFRAAQ KNIDRETSHV TMVVAELEKT LSGCPAVDSV VSLLDGVVEK LSVLKRKAVE SIQAEDESAK LCKRRIEHLK EHSSDQPAAA SVWKRKRMDR MMVEHLLRCG YYNTAVKLAR QSGIEDLVNI EMFLTAKEVE ESLERRETAT CLAWCHDNKS RLRKMKSCLE FSLRIQEFIE LIRQNKRLDA VRHARKHFSQ AEGSQLDEVR QAMGMLAFPP DTHISPYKDL LDPARWRMLI QQFRYDNYRL HQLGNNSVFT LTLQAGLSAI KTPQCYKEDG SSKSPDCPVC SRSLNKLAQP LPMAHCANSR LVCKISGDVM NENNPPMMLP NGYVYGYNSL LSIRQDDKVV CPRTKEVFHF SQAEKVYIM