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Recombinant human CNOT8 protein

CAT: 0112-ATGP2161-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2161-100Size:100 µg
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Description
CNOT8 belongs to the CAF1 family. It is a ubiquitous transcription factor required for a diverse set of processes and functions as part of the CCR-NOT complex. The CCR4-NOT complex functions as general transcription regulation complex. This complex contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8 and binds BTG2. Recombinant human CNOT8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
CCR4-NOT transcription complex subunit 8, CAF1, CALIF, hCAF1, POP2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.9 kDa (315aa) confirmed by MALDI-TOF
Additionnal Information
CNOT8, CCR4-NOT transcription complex subunit 8, CAF1, CALIF, hCAF1, POP2, ATGP2161-10 µg, ATGP2161-20 µg, ATGP2161-50 µg, ATGP2161-100 µg, ATGP2161-250 µg, ATGP2161-500 µg, ATGP2161-1 mg, ATGP2161-10, ATGP2161-20, ATGP2161-50, ATGP2161-100, ATGP2161-250, ATGP2161-500, ATGP2161-1
References & Citations
Morel A.-P., et al. (2003) J. Cell Sci. 116:2929-2936; ; Albert T.K., et al. (2000) Nucleic Acids Res. 28:809-817
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_004770
Uniprot Accession Number
Q9UFF9
Species
Human
AA Sequence
MPAALVE NSQVICEVWA SNLEEEMRKI REIVLSYSYI AMDTEFPGVV VRPIGEFRSS IDYQYQLLRC NVDLLKIIQL GLTFTNEKGE YPSGINTWQF NFKFNLTEDM YSQDSIDLLA NSGLQFQKHE EEGIDTLHFA ELLMTSGVVL CDNVKWLSFH SGYDFGYMVK LLTDSRLPEE EHEFFHILNL FFPSIYDVKY LMKSCKNLKG GLQEVADQLD LQRIGRQHQA GSDSLLTGMA FFRMKELFFE DSIDDAKYCG RLYGLGTGVA QKQNEDVDSA QEKMSILAII NNMQQ