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Recombinant human REXO2 protein

CAT: 0112-ATGP2152-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2152-100Size:100 µg
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Description
REXO2 is a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to uV-C-induced cell death through its role in the DNA repair process. Recombinant human REXO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.8 kDa (235aa) confirmed by MALDI-TOF
Additionnal Information
REXO2, Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN, ATGP2152-10 µg, ATGP2152-20 µg, ATGP2152-50 µg, ATGP2152-100 µg, ATGP2152-250 µg, ATGP2152-500 µg, ATGP2152-1 mg, ATGP2152-10, ATGP2152-20, ATGP2152-50, ATGP2152-100, ATGP2152-250, ATGP2152-500, ATGP2152-1
References & Citations
Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W . May 2000. Genome Res. 10 (5) : 703-13; ; Nguyen LH, Erzberger JP, Root J, Wilson DM .August 2000. J. Biol. Chem. 275 (34) : 25900-6.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_056338
Uniprot Accession Number
Q9Y3B8
Species
Human
AA Sequence
VREGGAA MAAGESMAQR MVWVDLEMTG LDIEKDQIIE MACLITDSDL NILAEGPNLI IKQPDELLDS MSDWCKEHHG KSGLTKAVKE STITLQQAEY EFLSFVRQQT PPGLCPLAGN SVHEDKKFLD KYMPQFMKHL HYRIIDVSTV KELCRRWYPE EYEFAPKKAA SHRALDDISE SIKELQFYRN NIFKKKIDEK KRKIIENGEN EKTVS

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