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Recombinant human C1D protein

CAT: 0112-ATGP2147-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2147-010Size:10 µg
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Description
Nuclear nucleic acid-binding protein C1D, also known as C1D, plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5. 8S rRNA; this function may include MPHOSPH6. This protein can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. This protein can induce apoptosis in a p53/TP53 dependent manner. Recombinant human C1D protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Nuclear nucleic acid-binding protein C1D, hC1D, LRP1, SuN-CoR, SuNCOR
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
18.4 kDa (164aa) confirmed by MALDI-TOF
Additionnal Information
C1D, Nuclear nucleic acid-binding protein C1D, hC1D, LRP1, SuN-CoR, SuNCOR, ATGP2147-10 µg, ATGP2147-20 µg, ATGP2147-50 µg, ATGP2147-100 µg, ATGP2147-250 µg, ATGP2147-500 µg, ATGP2147-1 mg, ATGP2147-10, ATGP2147-20, ATGP2147-50, ATGP2147-100, ATGP2147-250, ATGP2147-500, ATGP2147-1
References & Citations
Erdemir T., et al. (2002) J. Cell Sci. 115:207-216; ; Schilders G., et al. (2007) Nucleic Acids Res. 35:2564-2572
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_775269
Uniprot Accession Number
Q13901
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAGEEIN EDYPVEIHEY LSAFENSIGA VDEMLKTMMS VSRNELLQKL DPLEQAKVDL VSAYTLNSMF WVYLATQGVN PKEHPVKQEL ERIRVYMNRV KEITDKKKAG KLDRGAASRF VKNALWEPKS KNASKVANKG KSKS

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