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Recombinant human JDP2 protein

CAT: 0112-ATGP2068-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2068-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Jun dimerization protein 2, also known as JDP2, is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. This protein is involved in a variety of transcriptional responses associated with AP-1 such as uV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. JDP2 can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JuN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin. Recombinant human JDP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Jun dimerization protein 2, Jun dimerization protein 2, JuNDM2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
21.2 kDa (187aa) confirmed by MALDI-TOF
Additionnal Information
JDP2, Jun dimerization protein 2, Jun dimerization protein 2, JuNDM2, ATGP2068-10 µg, ATGP2068-20 µg, ATGP2068-50 µg, ATGP2068-100 µg, ATGP2068-250 µg, ATGP2068-500 µg, ATGP2068-1 mg, ATGP2068-10, ATGP2068-20, ATGP2068-50, ATGP2068-100, ATGP2068-250, ATGP2068-500, ATGP2068-1
References & Citations
Kawaida R., et al. (2003) J. Exp. Med. 197:1029-1035; ; Jin C., et al. (2006) Nat. Struct. Mol. Biol. 13:331-338;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT, 1mM EDTA, 250 mM imidazole
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_569736
Uniprot Accession Number
Q8WYK2
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK

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