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Recombinant human PHF11 protein

CAT: 0112-ATGP1790-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1790-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHD finger protein 11, also known as PHF11, is a regulator of TH1-type cytokine gene expression. The reduction in PHF11 expression seen with an AD-associated genotype could contribute to the strong TH2 responses that characterize many allergic individuals. PHF11 are associated with increased total serum IgE levels, asthma, and severe atopic dermatitis (AD) in children. Although PHF11 includes a plant homeodomain, a motif often found in transcriptional regulators, the function of PHF11 has not been investigated. Recombinant human PHF11 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
PHD finger protein 11, APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34, RP11-185C18.3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
39.7 kDa (351aa)
Additionnal Information
PHF11, PHD finger protein 11, APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34, RP11-185C18.3, ATGP1790-10 µg, ATGP1790-20 µg, ATGP1790-50 µg, ATGP1790-100 µg, ATGP1790-250 µg, ATGP1790-500 µg, ATGP1790-1 mg, ATGP1790-10, ATGP1790-20, ATGP1790-50, ATGP1790-100, ATGP1790-250, ATGP1790-500, ATGP1790-1
References & Citations
Clarke E., et al. (2008) J. Allergy Clin. Immunol. 121:1148-1154; ; Scanlan M.J., et al. (1999) Int. J. Cancer. 83:456-464;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_001035533
Uniprot Accession Number
Q9UIL8
Species
Human
AA Sequence
MAQASPPRPE RVLGASSPEA RPAQEALLLP TGVFQVAEKM EKRTCALCPK DVEYNVLYFA QSENIAAHEN CLLYSSGLVE CEDQDPLNPD RSFDVESVKK EIQRGRKLKC KFCHKRGATV GCDLKNCNKN YHFFCAKKDD AVPQSDGVRG IYKLLCQQHA QFPIIAQSAK FSGVKRKRGR KKPLSGNHVQ PPETMKCNTF IRQVKEEHGR HTDATVKVPF LKKCKEAGLL NYLLEEILDK VHSIPEKLMD ETTSESDYEE IGSALFDCRL FEDTFVNFQA AIEKKIHASQ QRWQQLKEEI ELLQDLKQTL CSFQENRDLM SSSTSISSLS Y

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