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Recombinant human RNF4 protein

CAT: 0112-ATGP1761-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1761-100Size:100 µg
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Description
E3 ubiquitin ligase RNF4, also known as RNF4, contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Recombinant human RNF4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
E3 ubiquitin ligase RNF4, RES4-26, SLX5, SNuRF
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.7 kDa (213aa) confirmed by MALDI-TOF
Additionnal Information
RNF4, E3 ubiquitin ligase RNF4, RES4-26, SLX5, SNuRF, ATGP1761-10 µg, ATGP1761-20 µg, ATGP1761-50 µg, ATGP1761-100 µg, ATGP1761-250 µg, ATGP1761-500 µg, ATGP1761-1 mg, ATGP1761-10, ATGP1761-20, ATGP1761-50, ATGP1761-100, ATGP1761-250, ATGP1761-500, ATGP1761-1
References & Citations
Kaiser F.J., et al. (2003) J. Biol. Chem. 278:38780-38785; ; Guo B., et al. (2009) Mol. Cell. Biol. 29:3204-3218
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT
Scientific Category
Ubiquitination
NCBI Accession Number
NP_001171938.1
Uniprot Accession Number
P78317
Species
Human
AA Sequence
MSTRKRR GGAINSRQAQ KRTREATSTP EISLEAEPIE LVETAGDEIV DLTCESLEPV VVDLTHNDSV VIVDERRRPR RNARRLPQDH ADSCVVSSDD EELSRDRDVY VTTHTPRNAR DEGATGLRPS GTVSCPICMD GYSEIVQNGR LIVSTECGHV FCSQCLRDSL KNANTCPTCR KKINHKRYHP IYI

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