Recombinant human CLIC2 protein

CAT: 0112-ATGP1020-500Size: 500 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP1020-500Size:500 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CLIC2, also known as, chloride intracellular channel protein 2, regulates cellular traffic of chloride ions, a critical component of all living cells. This protein is involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. It is detected in fetal liver and adult skeletal muscle tissue. It is a potential candidate for one of the many diseases linked to Xq28. Recombinant human CLIC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Chloride intracellular channel protein 2, CLIC2b, XAP121
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
30.5 kDa (267aa) confirmed by MALDI-TOF
Additionnal Information
CLIC2, Chloride intracellular channel protein 2, CLIC2b, XAP121, ATGP1020-10 µg, ATGP1020-20 µg, ATGP1020-50 µg, ATGP1020-100 µg, ATGP1020-250 µg, ATGP1020-500 µg, ATGP1020-1 mg, ATGP1020-10, ATGP1020-20, ATGP1020-50, ATGP1020-100, ATGP1020-250, ATGP1020-500, ATGP1020-1
References & Citations
Heiss N.S.. et al. (1997) Genomics. 45:224-228.; ; Thiemann A. et al. (1992) Nature. :356:57-60
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl and 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001280
Uniprot Accession Number
O15247
Species
Human
AA Sequence
MSGLRPGTQV DPEIELFVKA GSDGESIGNC PFCQRLFMIL WLKGVKFNVT TVDMTRKPEE LKDLAPGTNP PFLVYNKELK TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL NTPLLDEIDP DSAEEPPVSR RLFLDGDQLT LADCSLLPKL NIIKVAAKKY RDFDIPAEFS GVWRYLHNAY AREEFTHTCP EDKEIENTYA NVAKQKS

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