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Recombinant human FARS2 protein

CAT: 0112-ATGP1015-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1015-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phenylalanyl-tRNA synthetase 2, mitochondrial (PheRS), also known as FARS2, belongs to the class II aminoacyl- tRNA synthetase family. FARS2 is a mitochondrial matrix protein. Functioning as a monomer, FARS2 catalyzes the ATP-dependent conversion of L-phenylalanine and tRNA (Phe) to L-phenlalanyltRNA (Phe), an event that is crucial for proper translation and protein expression. Recombinant human FARS2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Phenylalanyl-tRNA synthetase 2 mitochondrial, Phenylalanyl-tRNA synthetase 2, mitochondrial, dJ520B18.2, FARS1, HSPC320, PheRS
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
50.6 kDa (436aa) confirmed by MALDI-TOF
Additionnal Information
FARS2, ATGP1015-10 µg, ATGP1015-20 µg, ATGP1015-50 µg, ATGP1015-100 µg, ATGP1015-250 µg, ATGP1015-500 µg, ATGP1015-1 mg, ATGP1015-10, ATGP1015-20, ATGP1015-50, ATGP1015-100, ATGP1015-250, ATGP1015-500, ATGP1015-1
References & Citations
Sasaki H M., et al. (2006) Proc Natl Acad Sci uSA. 103:14744-14749.; ; Bullard J M., et al. (1999) J Mol Biol. 288:567-577.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 1mM EDTA, 0.1M NaCl
Scientific Category
Metabolism
NCBI Accession Number
NP_006558.1
Uniprot Accession Number
O95363
Species
Human
AA Sequence
PAAECATQR APGSVVELLG KSYPQDDHSN LTRKVLTRVG RNLHNQQHHP LWLIKERVKE HFYKQYVGRF GTPLFSVYDN LSPVVTTWQN FDSLLIPADH PSRKKGDNYY LNRTHMLRAH TSAHQWDLLH AGLDAFLVVG DVYRRDQIDS QHYPIFHQLE AVRLFSKHEL FAGIKDGESL QLFEQSSRSA HKQETHTMEA VKLVEFDLKQ TLTRLMAHLF GDELEIRWVD CYFPFTHPSF EMEINFHGEW LEVLGCGVME QQLVNSAGAQ DRIGWAFGLG LERLAMILYD IPDIRLFWCE DERFLKQFCV SNINQKVKFQ PLSKYPAVIN DISFWLPSEN YAENDFYDLV RTIGGDLVEK VDLIDKFVHP KTHKTSHCYR ITYRHMERTL SQREVRHIHQ ALQEAAVQLL GVEGRF

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