Recombinant human DNAJC19 protein

CAT: 0112-ATGP0911-100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0112-ATGP0911-100Size:100 µg
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Description
DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA) . Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
15.1 kDa (135aa) confirmed by MALDI-TOF
Additionnal Information
TIMM-14, TIMM14, TIMM 14, TIM-14, TIM14, TIM 14, Pam-18, Pam18, Pam 18, Mitochondrial import inner membrane translocase subunit TIM-14, Mitochondrial import inner membrane translocase subunit TIM14, Mitochondrial import inner membrane translocase subunit TIM 14, DNAJC19, ATGP0911-10 µg, ATGP0911-20 µg, ATGP0911-50 µg, ATGP0911-100 µg, ATGP0911-250 µg, ATGP0911-500 µg, ATGP0911-1 mg, ATGP0911-010, ATGP0911-020, ATGP0911-050, ATGP0911-100, ATGP0911-250, ATGP0911-500, ATGP0911-01M
References & Citations
Davey KM., et al. (2006) J Med Genet. 43 (5) :385-93. ; ; Mokranjac D., et al. (2003) EMBO J. 22 (19) :4945-56.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_660304.1
Uniprot Accession Number
Q96DA6
Species
Human
AA Sequence
GRY VLQAMKHMEP QVKQVFQSLP KSAFSGGYYR GGFEPKMTKR EAALILGVSP TANKGKIRDA HRRIMLLNHP DKGGSPYIAA KINEAKDLLE GQAKK

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