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Recombinant human BDH2 protein

CAT: 0112-ATGP0882-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0882-020Size:20 µg
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Description
BDH2, also known as DHRS6, belongs to the short-chain dehydrogenases/reductases (SDR) family. This protein may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of BDH2 make it suitable to convert high levels of circulating 3-hydroxybutyrate into acetoacetate. Recombinant human BDH2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
3-hydroxybutyrate dehydrogenase type 2, DHRS6, EFA6R, FLJ13261, PRO20933, SDR15C1, uCPA-OR, uNQ6308
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
28.8 kDa (265aa) confirmed by MALDI-TOF
Additionnal Information
BDH2, 3-hydroxybutyrate dehydrogenase type 2, DHRS6, EFA6R, FLJ13261, PRO20933, SDR15C1, uCPA-OR, uNQ6308, ATGP0882-10 µg, ATGP0882-20 µg, ATGP0882-50 µg, ATGP0882-100 µg, ATGP0882-250 µg, ATGP0882-500 µg, ATGP0882-1 mg, ATGP0882-10, ATGP0882-20, ATGP0882-50, ATGP0882-100, ATGP0882-250, ATGP0882-500, ATGP0882-1
References & Citations
Guo K., et al. (2006) . J. Biol. Chem., 281: 10291-10297; ; Ito K., et al. (2006) . J. Mol. Biol., 355: 722-733.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Metabolism
NCBI Accession Number
NP_064524
Uniprot Accession Number
Q9BUT1
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGRLDGKVII LTAAAQGIGQ AAALAFAREG AKVIATDINE SKLQELEKYP GIQTRVLDVT KKKQIDQFAN EVERLDVLFN VAGFVHHGTV LDCEEKDWDF SMNLNVRSMY LMIKAFLPKM LAQKSGNIIN MSSVASSVKG VVNRCVYSTT KAAVIGLTKS VAADFIQQGI RCNCVCPGTV DTPSLQERIQ ARGNPEEARN DFLKRQKTGR FATAEEIAML CVYLASDESA YVTGNPVIID GGWSL