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Recombinant human RAB7A protein

CAT: 0112-ATGP0877-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0877-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ras-related protein Rab-7a, also known as RAB7A, is a member of the Ras superfamily of small Rab GTPases. RAB7A associates with the RIPL effector protein to control membrane trafficking from early to late endosome and to lysosomes. RAB7A has also been shown to regulate growth receptor endocytic trafficking, degradation, maturation of phagosome and autophagic vacuoles. Recombinant human RAB7A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Ras-related protein Rab-7a, RAB7, RAB7A member RAS oncogene family, CMT2B, Charcot-Marie-Tooth neuropathy 2B
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
25.6 kDa (227aa) confirmed by MALDI-TOF
Additionnal Information
Rab7a, Ras-related protein Rab-7a, RAB7, ATGP0877-10 µg, ATGP0877-20 µg, ATGP0877-50 µg, ATGP0877-100 µg, ATGP0877-250 µg, ATGP0877-500 µg, ATGP0877-1 mg, ATGP0877-10, ATGP0877-20, ATGP0877-50, ATGP0877-100, ATGP0877-250, ATGP0877-500, ATGP0877-1
References & Citations
Feng Y., et al. (1995) J Cell Biol. 131:1435-52.; ; Barbero P., et al. (2002) J Cell Biol. 156:511-8.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 100 mM NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_004628.4
Uniprot Accession Number
P51149
Species
Human
AA Sequence
MTSRKKVLLK VIILGDSGVG KTSLMNQYVN KKFSNQYKAT IGADFLTKEV MVDDRLVTMQ IWDTAGQERF QSLGVAFYRG ADCCVLVFDV TAPNTFKTLD SWRDEFLIQA SPRDPENFPF VVLGNKIDLE NRQVATKRAQ AWCYSKNNIP YFETSAKEAI NVEQAFQTIA RNALKQETEV ELYNEFPEPI KLDKNDRAKA SAESCSC

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