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Recombinant human PITPNA protein

CAT: 0112-ATGP0826-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0826-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phosphatidylinositol transfer protein alpha, also known PITPNA, is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. PITPNA is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase. Recombinant human PITPNA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Phosphatidylinositol transfer protein alpha isoform, PI-TP alpha, PITPN, VIB1A, PtdInsTP alpha
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
33.9 kDa (290aa) confirmed by MALDI-TOF
Additionnal Information
PITPNA, Phosphatidylinositol transfer protein alpha isoform, PI-TP alpha, PITPN, VIB1A, PtdInsTP alpha, ATGP0826-10 µg, ATGP0826-20 µg, ATGP0826-50 µg, ATGP0826-100 µg, ATGP0826-250 µg, ATGP0826-500 µg, ATGP0826-1 mg, ATGP0826-10, ATGP0826-20, ATGP0826-50, ATGP0826-100, ATGP0826-250, ATGP0826-500, ATGP0826-1
References & Citations
Monaco M E., et al. (1998) Biochem J. 335:175-179.; ; Aikawa Y., et al. (1999) J Biol Chem. 274:20569-20577.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 1mM EDTA
Scientific Category
Metabolism
NCBI Accession Number
NP_006215
Uniprot Accession Number
Q00169
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MVLLKEYRVI LPVSVDEYQV GQLYSVAEAS KNETGGGEGV EVLVNEPYEK DGEKGQYTHK IYHLQSKVPT FVRMLAPEGA LNIHEKAWNA YPYCRTVITN EYMKEDFLIK IETWHKPDLG TQENVHKLEP EAWKHVEAVY IDIADRSQVL SKDYKAEEDP AKFKSIKTGR GPLGPNWKQE LVNQKDCPYM CAYKLVTVKF KWWGLQNKVE NFIHKQERRL FTNFHRQLFC WLDKWVDLTM DDIRRMEEET KRQLDEMRQK DPVKGMTADD

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