Recombinant human PITPNB protein

• Description :

  Phosphatidylinositol transfer protein beta isoform, also known PITPNB, is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. PITPNB mobilizes PI from the endoplasmic recticulum and regulates the release of PI from stored vesicles in the Golgi network. PITPNB is widely expressed in various tissues. Recombinant human PITPNB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

• Product Name Alternative :

  Phosphatidylinositol transfer protein beta isoform, PI-TP-beta, PtdInsTP beta, VIB1B

• Expression System :

  E.coli

• Antigen Species :

  Human

• Tag :

  His-Tag

• Applications :

  SDS-PAGE

• Concentration :

  1 mg/mL (determined by Bradford assay)

• Purity :

  > 95% by SDS-PAGE

• Molecular Weight :

  33.7 kDa (291aa) confirmed by MALDI-TOF

• Additionnal Information :

  PITPNB, Phosphatidylinositol transfer protein beta isoform, PI-TP-beta, PtdInsTP beta, VIB1B, ATGP0778-10 µg, ATGP0778-20 µg, ATGP0778-50 µg, ATGP0778-100 µg, ATGP0778-250 µg, ATGP0778-500 µg, ATGP0778-1 mg, ATGP0778-10, ATGP0778-20, ATGP0778-50, ATGP0778-100, ATGP0778-250, ATGP0778-500, ATGP0778-1

• References & Citations :

  Sequi B., et al. (2002) Biochem J. 366:23-34.; ; Rikova K., et al. (2007) Cell. 131:1190-1203.;

• Storage Conditions :

  Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

• Formulation :

  Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

• Scientific Category :

  Metabolism

• NCBI Accession Number :

  NP_036531

• Uniprot Accession Number :

  P48739

• Species :

  Human

• AA Sequence :

  MGSSHHHHHH SSGLVPRGSH MVLIKEFRVV LPCSVQEYQV GQLYSVAEAS KNETGGGEGI EVLKNEPYEK DGEKGQYTHK IYHLKSKVPA FVRMIAPEGS LVFHEKAWNA YPYCRTIVTN EYMKDDFFIK IETWHKPDLG TLENVHGLDP NTWKTVEIVH IDIADRSQVE PADYKADEDP ALFQSVKTKR GPLGPNWKKE LANSPDCPQM CAYKLVTIKF KWWGLQSKVE NFIQKQEKRI FTNFHRQLFC WIDKWIDLTM EDIRRMEDET QKELETMRKR GSVRGTSAAD V