Products for Research Use Only
RegisterLogin

Recombinant human SH2D1A protein

CAT: 0112-ATGP0783-020Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP0783-020Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
16.3 kDa (148aa) confirmed by MALDI-TOF
Additionnal Information
SH2D1A, SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD, ATGP0783-10 µg, ATGP0783-20 µg, ATGP0783-50 µg, ATGP0783-100 µg, ATGP0783-250 µg, ATGP0783-500 µg, ATGP0783-1 mg, ATGP0783-10, ATGP0783-20, ATGP0783-50, ATGP0783-100, ATGP0783-250, ATGP0783-500, ATGP0783-1
References & Citations
Schwartzberg PL., et al. (2010) Immunity. 32 (2) :253-65.; ; Lenardo MJ., et al (2009) J Clin Invest. 119 (10) :2976-89;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Scientific Category
Immunology
NCBI Accession Number
NP_002342
Uniprot Accession Number
O60880
Species
Human
AA Sequence
MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP

Related Products

CatalogName
ATGD0106-010SH2D1A cDNA
ATGP3657-010Recombinant human SH2D1B protein
ATGP3657-250Recombinant human SH2D1B protein
ATGP3657-050Recombinant human SH2D1B protein
TPM0701-500Recombinant human TPMT protein
TPM0701-100Recombinant human TPMT protein
TPD0501-020Recombinant human TPD52L1 protein
SNP0902-500Recombinant human Syntaphilin protein
SNP0901-050Recombinant human SNAP23 protein
SNP0801-020Recombinant human SNAP25 protein

Alternative Products

CatalogName
ARP3908-01Recombinant Human SH2D1A Protein
RP028414SH2D1A Recombinant Protein (Human)
GTR18909815SH2D1A Recombinant Protein
P4218-01Recombinant Human SH2D1A
TP304723MSH2D1A (NM_002351) Human Recombinant Protein
GTR18906000-01Human SH2D1A protein
RP228515SH2D1A Recombinant Protein (Rat)
RP171566SH2D1A Recombinant Protein (Mouse)
KMH1713-01Recombinant Human SH2D1A Protein, His Tag
PR02248Recombinant Human SH2D1A Protein, N-His

Popular Products