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Recombinant human PFDN2 protein

CAT: 0112-ATGP0774-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0774-250Size:250 µg
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Description
PFDN2 (Prefoldin subunit 2) is a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. This protein binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. And binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Recombinant human PFDN2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Prefoldin subunit 2, PFD2, HSPC231
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.8 kDa (174aa) confirmed by MALDI-TOF
Additionnal Information
PFDN2, Prefoldin subunit 2, PFD2, HSPC231, ATGP0774-10 µg, ATGP0774-20 µg, ATGP0774-50 µg, ATGP0774-100 µg, ATGP0774-250 µg, ATGP0774-500 µg, ATGP0774-1 mg, ATGP0774-10, ATGP0774-20, ATGP0774-50, ATGP0774-100, ATGP0774-250, ATGP0774-500, ATGP0774-1
References & Citations
Vainberg I.E., et al. (1998) Cell 93:863-873; ; Grebenova D., et al. (2006) Blood Cells Mol. Dis. 37 (3) :210-7.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 50 mM NaCl
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_036526
Uniprot Accession Number
Q9UHV9
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MAENSGRAGK SSGSGAGKGA VSAEQVIAGF NRLRQEQRGL ASKAAELEME LNEHSLVIDT LKEVDETRKC YRMVGGVLVE RTVKEVLPAL ENNKEQIQKI IETLTQQLQA KGKELNEFRE KHNIRLMGED EKPAAKENSE GAGAKASSAG VLVS

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