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Recombinant human RCN1 protein

CAT: 0112-ATGP0672-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0672-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Reticulocalbin 1 (RCN1) is a calcium-binding protein. It binds calcium and may regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. The protein contains six conserved regions with similarity to a high affinity Ca (+2) -binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane. Recombinant human RCN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Reticulocalbin-1, PIG20, RCAL, RCN, Reticulocalbin-1, Reticulocalbin 1, Reticulocalbin1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
40.4 kDa (341aa) confirmed by MALDI-TOF (Real Molecular weight on SDS-PAGE will be shift up)
Additionnal Information
RCN1, Reticulocalbin-1, PIG20, RCAL, RCN, Reticulocalbin-1, Reticulocalbin 1, Reticulocalbin1, ATGP0672-10 µg, ATGP0672-20 µg, ATGP0672-50 µg, ATGP0672-100 µg, ATGP0672-250 µg, ATGP0672-500 µg, ATGP0672-1 mg, ATGP0672-10, ATGP0672-20, ATGP0672-50, ATGP0672-100, ATGP0672-250, ATGP0672-500, ATGP0672-1
References & Citations
Tachikui., et al. (1997) M. J. Biochem. 121 (1) :145-9.; ; Gloria K., et al. (2006) Plant Physiology 141:1617-1629;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 100 mM NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_002892
Uniprot Accession Number
Q15293
Species
Human
AA Sequence
ELEK PTVRKERVVR PDSELGERPP EDNQSFQYDH EAFLGKEDSK TFDQLTPDES KERLGKIVDR IDNDGDGFVT TEELKTWIKR VQKRYIFDNV AKVWKDYDRD KDDKISWEEY KQATYGYYLG NPAEFHDSSD HHTFKKMLPR DERRFKAADL NGDLTATREE FTAFLHPEEF EHMKEIVVLE TLEDIDKNGD GFVDQDEYIA DMFSHEENGP EPDWVLSERE QFNEFRDLNK DGKLDKDEIR HWILPQDYDH AQAEARHLVY ESDKNKDEKL TKEEILENWN MFVGSQATNY GEDLTKNHDE L

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