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Recombinant human GRHPR protein

CAT: 0112-ATGP0577-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0577-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GRHPR, also known as GLXR, is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family of proteins. Localizing to the cytosol, GRHPR is ubiquitously expressed with highest expression levels found in liver. The protein has widespread tissue expression and has a role in metabolism. GRHPR is an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. Recombinant human GRHPR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
Glyoxylate reductase/hydroxypyruvate reductase, GLXR, GLYD, PH2, Glyoxylate reductase/hydroxypyruvate reductase glycerate 2 dehydrogenase, Glyoxylate reductase/hydroxypyruvate reductase, OTTHuMP00000046131, PH 2, Primary hyperoxaluria type 2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
37.8 kDa (348aa) confirmed by MALDI-TOF
Additionnal Information
GRHPR, Glyoxylate reductase/hydroxypyruvate reductase, GLXR, GLYD, PH2, Glyoxylate reductase/hydroxypyruvate reductase glycerate 2 dehydrogenase, Glyoxylate reductase/hydroxypyruvate reductase, OTTHuMP00000046131, PH 2, Primary hyperoxaluria type 2, ATGP0577-10 µg, ATGP0577-20 µg, ATGP0577-50 µg, ATGP0577-100 µg, ATGP0577-250 µg, ATGP0577-500 µg, ATGP0577-1 mg, ATGP0577-10, ATGP0577-20, ATGP0577-50, ATGP0577-100, ATGP0577-250, ATGP0577-500, ATGP0577-1
References & Citations
Booth MP., et al. (2006) J Mol Biol. 360 (1) :178-89. ; ; Genolet R., et al. (2005) J Biol Chem. 280 (25) :24143-52.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_036335
Uniprot Accession Number
Q9UBQ7
Species
Human
AA Sequence
MRPVRLMKVF VTRRIPAEGR VALARAADCE VEQWDSDEPI PAKELERGVA GAHGLLCLLS DHVDKRILDA AGANLKVIST MSVGIDHLAL DEIKKRGIRV GYTPDVLTDT TAELAVSLLL TTCRRLPEAI EEVKNGGWTS WKPLWLCGYG LTQSTVGIIG LGRIGQAIAR RLKPFGVQRF LYTGRQPRPE EAAEFQAEFV STPELAAQSD FIVVACSLTP ATEGLCNKDF FQKMKETAVF INISRGDVVN QDDLYQALAS GKIAAAGLDV TSPEPLPTNH PLLTLKNCVI LPHIGSATHR TRNTMSLLAA NNLLAGLRGE PMPSELKL

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