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Recombinant human S100P protein

CAT: 0112-ATGP0565-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0565-100Size:100 µg
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Description
S100P is a Ca2+ binding protein that belongs to S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100P is involved in diverse biological functions but the exact role or mechanism of its action is still largely unknown. upon binding of calcium ions S100P undergoes a conformational change that results in an exposure of a hydrophobic surface which allows the interaction with specific target proteins. Recombinant human S100P protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
S100 calcium binding protein P, S100E, S100 calcium binding protein P MIG9, Migration inducing gene 9, Protein S100P, S100 calcium binding protein P, S100 P.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
12.6 kDa (115aa) confirmed by MALDI-TOF
Additionnal Information
S100P, S100 calcium binding protein P, S100E, S100 calcium binding protein P MIG9, Migration inducing gene 9, Protein S100P, S100 calcium binding protein P, S100 P., ATGP0565-10 µg, ATGP0565-20 µg, ATGP0565-50 µg, ATGP0565-100 µg, ATGP0565-250 µg, ATGP0565-500 µg, ATGP0565-1 mg, ATGP0565-10, ATGP0565-20, ATGP0565-50, ATGP0565-100, ATGP0565-250, ATGP0565-500, ATGP0565-1
References & Citations
Dowen S.E., et al (2005) Am. J. Pathol. 166:81-92; ; Koltzscher M, et al (2003) Mol Biol Cell. 14 (6) :2372-84;
Other References
Chiba M, et al. Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma. (Oncol Rep. 2017) {https://pubmed.ncbi.nlm.nih.gov/28260012/}
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 50 mM NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_005971.1
Uniprot Accession Number
P25815
Species
Human
AA Sequence
MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK

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