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Recombinant human SURF1 protein

CAT: 0112-ATGP0451-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0451-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SuRF1, also known as surfeit 1, is a member of the SuRF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. This protein is localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Defect in SuRF1 is a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. Recombinant SuRF1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Surfeit 1, Surfeit 1 SuRF 1, SuRF1, Surfeit locus protein 1, SURF1 cytochrome c oxidase assembly factor, SHY1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
24.3 kDa (215aa) confirmed by MALDI-TOF
Additionnal Information
SHY 1, SHY1, SuRF 1, SuRF1, SuRF-1, SURF1 cytochrome c oxidase assembly factor, Surfeit 1, Surfeit 1 SuRF 1, Surfeit locus protein 1, Surfeit locus protein1, Surfeit1, Surfeit-1, ATGP0451-10 µg, ATGP0451-20 µg, ATGP0451-50 µg, ATGP0451-100 µg, ATGP0451-250 µg, ATGP0451-500 µg, ATGP0451-1 mg, ATGP0451-010, ATGP0451-020, ATGP0451-050, ATGP0451-100, ATGP0451-250, ATGP0451-500, ATGP0451-01M
References & Citations
Pequignot MO., et al. (2001) Hum Mutat. 17 (5) :374-81. ; ; Zhu Z., et al. (1998) Nat Genet. 20 (4) :337-43. ;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Scientific Category
Redox Proteins
NCBI Accession Number
NP_003163
Uniprot Accession Number
Q15526
Species
Human
AA Sequence
MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ

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