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Recombinant human SAR1A protein

CAT: 0112-ATGP0347-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0347-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SAR1a gene homolog 1, also known as SAR1A, belongs to the small GTPase superfamily. Sar1 is an essential component of COPII vesicle coats involved in export of cargo from the ER. The GTPase activity of Sar1 functions as a molecular switch to control protein-protein and protein-lipid interactions that direct vesicle budding from the ER. GDP-bound Sar1 interacts with the membrane-bound exchange factor Sec12 and exchanges its bound GDP for GTP. Recombinant human SAR1A, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
SARA 1, Sara, SAR1a gene homolog 1 COPII associated small GTPase, SAR1a gene homolog 1 (S. cerevisiae), SAR1A, SAR1 homolog A (S. cerevisiae), SAR1 gene homolog A, SAR 1, Masra 2, GTP binding protein SAR1a, COPII-associated small GTPase
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.5 kDa (218aa) confirmed by MALDI-TOF
Additionnal Information
COPII-associated small GTPase, GTP binding protein SAR1a, Masra 2, Masra2, SAR 1, SAR1, SAR1 gene homolog A, SAR1 homolog A (S. cerevisiae), SAR1A, SAR1a gene homolog (S cerevisiae) 1, SAR1a gene homolog (S. cerevisiae) 1, SAR1a gene homolog 1, SAR1a gene homolog 1 (S cerevisiae), SAR1a gene homolog 1 (S. cerevisiae), SAR1a gene homolog 1 COPII associated small GTPase, Sara, SARA 1, SARA1, ATGP0347-10 µg, ATGP0347-20 µg, ATGP0347-50 µg, ATGP0347-100 µg, ATGP0347-250 µg, ATGP0347-500 µg, ATGP0347-1 mg, ATGP0347-010, ATGP0347-020, ATGP0347-050, ATGP0347-100, ATGP0347-250, ATGP0347-500, ATGP0347-01M
References & Citations
Jones B., et al. (2003) Nat Genet. 34 (1) :29-31. ; ; Bi X., et al. (2007) Dev Cell. 13 (5) :635-45. ;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_064535
Uniprot Accession Number
Q9NR31
Species
Human
AA Sequence
MSFIFEWIYN GFSSVLQFLG LYKKSGKLVF LGLDNAGKTT LLHMLKDDRL GQHVPTLHPT SEELTIAGMT FTTFDLGGHE QARRVWKNYL PAINGIVFLV DCADHSRLVE SKVELNALMT DETISNVPIL ILGNKIDRTD AISEEKLREI FGLYGQTTGK GNVTLKELNA RPMEVFMCSV LKRQGYGEGF RWLSQYID

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