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Recombinant human TBCA protein

CAT: 0112-ATGP0333-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0333-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. Recombinant human TBCA protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Tubulin folding cofactor A, Tubulin folding cofactor A, chaperonin cofactor a, tubulin specific chaperone a, TBCA, Tubulin folding cofactor A CFA, Co chaperonin associated with a & b tubulin, Cofactor A, TCP1 chaperonin cofactor A, Tubulin cofactor a.
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
12.8 kDa (108aa) confirmed by MALDI-TOF
Additionnal Information
TBCA, Tubulin folding cofactor A, Tubulin folding cofactor A, chaperonin cofactor a, tubulin specific chaperone a, TBCA, Tubulin folding cofactor A CFA, Co chaperonin associated with a & b tubulin, Cofactor A, TCP1 chaperonin cofactor A, Tubulin cofactor a., ATGP0333-10 µg, ATGP0333-20 µg, ATGP0333-50 µg, ATGP0333-100 µg, ATGP0333-250 µg, ATGP0333-500 µg, ATGP0333-1 mg, ATGP0333-10, ATGP0333-20, ATGP0333-50, ATGP0333-100, ATGP0333-250, ATGP0333-500, ATGP0333-1
References & Citations
Nolasco S., et al. (2005) . FEBS Lett. 579 (17) :3515-24; ; Tian G., et al. (1996) . Cell. 86 (2) :287-96;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_004598.1
Uniprot Accession Number
O75347
Species
Human
AA Sequence
MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA

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