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NUDT1 cDNA

CAT: 0112-ATGD0090-010Size: 10 µgDry Ice: NoHazardous: No
CAT#:0112-ATGD0090-010Size:10 µg
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Description
NuDT1 is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. It is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. And this protein expressed at much higher levels in proliferating cells than in resting cells
Product Name Alternative
MTH1
Chromosomal Location
7p22
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGGGCGCCT CCAGGCTCTA TACCCTGGTG CTGGTCCTGC AGCCTCAGCG AGTTCTCCTG GGCATGAAAA AGCGAGGCTT CGGGGCCGGC CGGTGGAATG GCTTTGGGGG CAAAGTGCAA GAAGGAGAGA CCATCGAGGA TGGGGCTAGG AGGGAGCTGC AGGAGGAGAG CGGTCTGACA GTGGACGCCC TGCACAAGGT GGGCCAGATC GTGTTTGAGT TCGTGGGCGA GCCTGAGCTC ATGGACGTGC ATGTCTTCTG CACAGACAGC ATCCAGGGGA CCCCCGTGGA GAGCGACGAA ATGCGCCCAT GCTGGTTCCA GCTGGATCAG ATCCCCTTCA AGGACATGTG GCCCGACGAC AGCTACTGGT TTCCACTCCT GCTTCAGAAG AAGAAATTCC ACGGGTACTT CAAGTTCCAG GGTCAGGACA CCATCCTGGA CTACACACTC CGCGAGGTGG ACACGGTCTA G
Additionnal Information
NUDT1, MTH1, ATGD0090-10 µg, ATGD0090-20 µg, ATGD0090-50 µg, ATGD0090-100 µg, ATGD0090-250 µg, ATGD0090-500 µg, ATGD0090-1 mg, ATGD0090-010, ATGD0090-020, ATGD0090-050, ATGD0090-100, ATGD0090-250, ATGD0090-500, ATGD0090-01M
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Enzymes & Proteases
Omim
600312
NCBI Accession Number
NP_945191.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_198953.1
DNA Size
471bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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