Products for Research Use Only
RegisterLogin

NUDT1 Protein

CAT: 0247-OPPA02614-5UGSize: 5 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OPPA02614-5UGSize:5 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Gene Name
Nudix (nucleoside diphosphate linked moiety X) -type motif 1
Gene Aliases
MTH1
Gene ID
4521
Accession Number
NP_002443.3
Reactivity
Human
Target
NUDT1 is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. NUDT1 is found mostly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Moreover, NUDT1 is expressed at much higher levels in proliferating cells than in resting cells. Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations which may result in carcinogenesis or neurodegeneration.
Type
Protein
Source
E. coli
Sequence
MGSSHHHHHH SSGLVPRGSH MGASRLYTLV LVLQPQRVLL GMKKRGFGAG RWNGFGGKVQ EGETIEDGAR RELQEESGLT VDALHKVGQI VFEFVGEPEL MDVHVFCTDS IQGTPVESDE MRPCWFQLDQ IPFKDMWPDD SYWFPLLLQK KKFHGYFKFQ GQDTILDYTL REVDTV.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
The NUDT1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT and 100mM NaCl. Physical appearance: Sterile Filtered colorless solution.
Reconstitution
NUDT1 should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Notes
Formerly GWB-BSP261
Protein Length
Recombinant
NCBI Gene Symbol
NUDT1
Protein Name
7,8-dihydro-8-oxoguanine triphosphatase
Gene Name URL
NUDT1

Related Products

CatalogName
OACA10375-100UGNUDT1 Antibody
OAAN01311-100ULNUDT1 Antibody
OACA10375-50UGNUDT1 Antibody
OAAN01311-200ULNUDT1 Antibody
OAAN01311-50ULNUDT1 Antibody
OAAJ07825-100ULNUDT1 Antibody
OKEH01689-96WNUDT1 ELISA Kit (Human)
OKEH05139-96WNUDT1 ELISA Kit (Mouse)
OKEH06003-96WNUDT1 ELISA Kit (Rat)
ARP49190_P050-25ULNUDT1 Antibody - middle region

Alternative Products

CatalogName
GTR18883808-01Human NUDT1 protein
32-2619-20NUDT1 Recombinant Protein
ARP3213-01Recombinant Human NUDT1 Protein
80R-1504NUDT1 protein (His tag)
RP021823NUDT1 Recombinant Protein (Human)
MBS8416336-01Human NUDT1 Protein Lysate
RP155363NUDT1 Recombinant Protein (Mouse)
RP214766NUDT1 Recombinant Protein (Rat)
TP501165Nudt1 (NM_008637) Mouse Recombinant Protein
ATGP0742-100Recombinant human NUDT1/MTH1 protein

Popular Products