Products for Research Use Only
RegisterLogin

Human TREM2 antibody

CAT: 0112-ATGA0607-050Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGA0607-050Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system) .
Product Name Alternative
Ttriggering receptor expressed on myeloid cells 2 isoform 1, Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on myeloid cells 2a, TREM-2, Trem2a, Trem2b, Trem2c
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human TREM2 (19-161aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT1E7
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF, FACS
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
ATGA0607-10 µg, ATGA0607-20 µg, ATGA0607-50 µg, ATGA0607-100 µg, ATGA0607-250 µg, ATGA0607-500 µg, ATGA0607-1 mg, ATGA0607-010, ATGA0607-020, ATGA0607-050, ATGA0607-100, ATGA0607-250, ATGA0607-500, ATGA0607-01M , ATGA0605-10 µg, ATGA0605-20 µg, ATGA0605-50 µg, ATGA0605-100 µg, ATGA0605-250 µg, ATGA0605-500 µg, ATGA0605-1 mg, ATGA0605-010, ATGA0605-020, ATGA0605-050, ATGA0605-100, ATGA0605-250, ATGA0605-500, ATGA0605-01M, ATR0917-10 µg, ATR0917-20 µg, ATR0917-50 µg, ATR0917-100 µg, ATR0917-250 µg, ATR0917-500 µg, ATR0917-1 mg, ATR0917-010, ATR0917-020, ATR0917-050, ATR0917-100, ATR0917-250, ATR0917-500, ATR0917-01M
References & Citations
N.Diaye EN, et al., (2009) J Cell Biol. 184 (2) :215-23.; ; Piccio L, et al., (2008) Brain. 131 (11) :3081-91.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Scientific Category
Immunology, Neuroscience
NCBI Accession Number
NP_061838
Uniprot Accession Number
Q9NZC2
WB Description
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TREM2 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1 : 293T cell lysate; ; Lane 2 : TREM2 19-161aa Transfected 293T cell lysate
FACS Description
Flow cytometry analysis of TREM2 in Hep3B cells. The cell was stained with ATGA0607 at 2-5ug for 1x10^6cells (red) . A Goat anti mouse IgG (Alexa fluor 488) was used as the secondary antibody. Mouse monoclonal IgG was used as the isotype control (dark gray), cells without incubation with primary and secondary antibody was used as the negative control (light gray) .
IF Description
ICC/IF analysis of TREM2 in HepG2 cells. The cell was stained with ATGA0607 (1:100) . The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue) .ICC/IF analysis of TREM2 in Raw264.7 cells. The cell was stained with ATGA0607 (1:100) . The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue) .{2504070001526390.jpg}

Related Products

CatalogName
ATGP4104-500Recombinant human TREM2 protein
ATGP4104-250Recombinant human TREM2 protein
ATGP4104-020Recombinant human TREM2 protein
ATGP4104-010Recombinant human TREM2 protein
ATGP2452-050Recombinant human TREM2 protein
ATGP2452-250Recombinant human TREM2 protein
ATGP2452-010Recombinant human TREM2 protein
ATGP4104-100Recombinant human TREM2 protein
ATGP4104-050Recombinant human TREM2 protein
ATGP0970-020Recombinant human TREX2 protein

Alternative Products

CatalogName
E55A15780Human TREM2 Antibody
GTR18685831-01TREM2 Human Monoclonal Antibody
E55A10806Human TREM2 Antibody , PE
E55A09799Human TREM2 Antibody , PerCP
MBS1569217-01Anti-Human TREM2 Antibody
NC218-01Human TREM2 Antibody (5G12)
E55A07785Human TREM2 Antibody , FITC
GTR18777963-01Human/Mouse TREM2 Antibody
E55A08792Human TREM2 Antibody , APC
ARO-A16186-01Human TREM2 Monoclonal Antibody

Popular Products