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Recombinant human TREX2 protein

CAT: 0112-ATGP0970-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0970-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TREX2 is an enzyme containing 3-prime-to-5-prime exonuclease activity and removes mismatched, modified, fragmented, and normal nucleotides to generate the appropriate 3-prime termini for subsequent steps in the DNA metabolic pathways. This enzyme is involved in DNA replication, repair, and recombination. Recombinant human TREX2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Three prime repair exonuclease 2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
28.0 kDa (256aa) confirmed by MALDI-TOF
Additionnal Information
TREX2, Three prime repair exonuclease 2, ATGP0970-10 µg, ATGP0970-20 µg, ATGP0970-50 µg, ATGP0970-100 µg, ATGP0970-250 µg, ATGP0970-500 µg, ATGP0970-1 mg, ATGP0970-10, ATGP0970-20, ATGP0970-50, ATGP0970-100, ATGP0970-250, ATGP0970-500, ATGP0970-1
References & Citations
Parra D., et al. (2009) Cancer Res. 69 (16) :6676-84.; ; Perrino FW., et al. (2008) J Biol Chem. 283 (31) :21441-52.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_542432
Uniprot Accession Number
Q9BQ50
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MSEAPRAETF VFLDLEATGL PSVEPEIAEL SLFAVHRSSL ENPEHDESGA LVLPRVLDKL TLCMCPERPF TAKASEITGL SSEGLARCRK AGFDGAVVRT LQAFLSRQAG PICLVAHNGF DYDFPLLCAE LRRLGARLPR DTVCLDTLPA LRGLDRAHSH GTRARGRQGY SLGSLFHRYF RAEPSAAHSA EGDVHTLLLI FLHRAAELLA WADEQARGWA HIEPMYLPPD DPSLEA

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