Products for Research Use Only
RegisterLogin

Human Thioredoxin-2 antibody

CAT: 0112-ATGA0427-050Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGA0427-050Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The Thioredoxin2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
Product Name Alternative
MTRX, TRX2, MT-TRX, Thioredoxin2, mitochondrial thioredoxin, thioredoxin 2 precursor, Thioredoxin mitochondrial, TRX 2, TXN 2, TXN2, Thioredoxin-2
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human Thioredoxin2 (60-166aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
AT1B1
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
Thioredoxin2, MTRX, TRX2, MT-TRX, Thioredoxin2, mitochondrial thioredoxin, thioredoxin 2 precursor, Thioredoxin mitochondrial, TRX 2, TXN 2, TXN2, Thioredoxin-2, ATGA0427-10 µg, ATGA0427-20 µg, ATGA0427-50 µg, ATGA0427-100 µg, ATGA0427-250 µg, ATGA0427-500 µg, ATGA0427-1 mg, ATGA0427-10, ATGA0427-20, ATGA0427-50, ATGA0427-100, ATGA0427-250, ATGA0427-500, ATGA0427-1
References & Citations
Wang Z., et al. (2007) Rapid Commun Mass Spectrom. 21 (22) : 3658-66.; ; Zhang H., et al. (2007) Arch Biochem biophys. 465 (1) : 119-26.; ; Holmgren, A. (1979) Journal of Biological Chemistry. 254, 9627-9632.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Scientific Category
Signal Transduction
NCBI Accession Number
NP_036605
Uniprot Accession Number
Q99757
WB Description
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Thioredoxin2 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ; ; Lane 1 : HepG2 cell lysate ; ; Lane 2 : HeLa cell lysate ; ; Lane 3 : Raji cell lysate ; ; Lane 4 : K562 cell lysate ; ; Lane 5 : Jurkat cell lysate ; ; Lane 6 : A431 cell lysate ; ; Lane 7 : MCF7 cell lysate ; ; Lane 8 : THP1 cell lysate Recombinant protein (50ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Thioredoxin2 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ; ; Lane 1 : Recombinant human Thioredoxin1 protein ; ; Lane 2 : Recombinant human Thioredoxin2 protein {ATGA0427-WB2.jpg}
IF Description
ICC/IF analysis of TXN2 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human TXN2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green) .

Related Products

CatalogName
TRX0801-500Recombinant human Thioredoxin-2 protein
TRX0801-100Recombinant human Thioredoxin-2 protein
TRX0801-020Recombinant human Thioredoxin-2 protein
ATGA0451-100Human Thioredoxin Reductase 1/TRXR1 antibody
ATGA0451-050Human Thioredoxin Reductase 1/TRXR1 antibody
ATGP0530-020Recombinant human Thioredoxin-1 protein
TRX0501-500Recombinant human Thioredoxin-1 protein
TRX0501-100Recombinant human Thioredoxin-1 protein
ATGP0530-500Recombinant human Thioredoxin-1 protein
ATGP0530-100Recombinant human Thioredoxin-1 protein

Alternative Products

CatalogName
30019-05111Human Thioredoxin-2 (TXN2) Antibody
GWB-9904C9Thioredoxin Human, Antibody
30019-05121Human Thioredoxin-2 (TXN2) Antibody (Biotin Conjugate)
MBS712517-01Rabbit anti-human thioredoxin 2 polyclonal Antibody
32251-05111Human Thioredoxin (TXN) Antibody
30019-05161Human Thioredoxin-2 (TXN2) AssayLite™ Antibody (APC Conjugate)
30019-05141Human Thioredoxin-2 (TXN2) AssayLite™ Antibody (FITC Conjugate)
MBS713034-01Rabbit anti-human thioredoxin reductase 2 polyclonal Antibody
30019-05171Human Thioredoxin-2 (TXN2) AssayLite™ Antibody (PerCP Conjugate)
30019-05151Human Thioredoxin-2 (TXN2) AssayLite™ Antibody (RPE Conjugate)

Popular Products