Human FBP2 antibody

CAT: 0112-ATGA0235-100Size: 100 µLDry Ice: NoHazardous: No
CAT#:0112-ATGA0235-100Size:100 µL
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Description
FBP2 (Fructose-1, 6-bisphosphatase isozyme 2) is a 339 amino acid protein. FBP2 belongs to the FBPase class 1 family. The hydrolysis of fructose-1, 6-bisphosphate to fructose-6-phosphate is a key reaction of carbohydrate metabolism. The enzyme that catalyzes this reaction appears to be present in all forms of living organisms. FBPase is encoded by two genes, FBP1 and FBP2, which express the liver and muscle isoforms, respectively. FBPase is regulated by AMP inhibition in most species. Inhibition of FBPase by AMP affects the turnover of bound substrate and not its affinity for substrate.
Product Name Alternative
Fructose-16-bisphosphatase isozyme 2, Fructose-1,6-bisphosphatase isozyme 2
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human FBP2 (1-339aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT1E11
Conjugation
Unconjugated
Applications
ELISA, WB
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
FBP2, ATGA0235-10 µg, ATGA0235-20 µg, ATGA0235-50 µg, ATGA0235-100 µg, ATGA0235-250 µg, ATGA0235-500 µg, ATGA0235-1 mg, ATGA0235-10, ATGA0235-20, ATGA0235-50, ATGA0235-100, ATGA0235-250, ATGA0235-500, ATGA0235-1
References & Citations
Dzugaj, A., et al. (1980) Biochim Biophys Acta 614: 407-412.; ; Marcus, F., et al. (1987) Arch Biol Med Exp 20: 371-378.; ; Matsuura, T., et al. (2002) Mol Genet Metab 76: 207-210.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Scientific Category
Metabolism
NCBI Accession Number
NP_003828
Uniprot Accession Number
O00757
WB Description
The cell lysate of mouse muscle (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human FBP2 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

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