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Atorvastatin calcium

CAT: 1139-134523-03-8-01Size: 25 KgDry Ice: NoHazardous: No
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CAT#:1139-134523-03-8-01Size:25 Kg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atorvastatin calcium (CAS: 134523-03-8) is a calcium salt form of atorvastatin, a synthetic lipid-lowering agent belonging to the statin class. It is a white to off-white crystalline powder, insoluble in water, slightly soluble in methanol, and soluble in dimethyl sulfoxide. Atorvastatin calcium (CAS: 134523-03-8) acts by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in cholesterol biosynthesis, thereby reducing the production of cholesterol in the liver.
Synonyms
Atorvastatin Ca, Calcium Atorvastatin, (3R,5R) -7-[2- (4-Fluorophenyl) -3-phenyl-4- (phenylcarbamoyl) -5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt, Atorvastatinum calcium, Atorvastatin calcium salt, (3R,5R) -7-[2- (4-Fluorophenyl) -3-phenyl-4- (phenylcarbamoyl) -5-isopropyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium
HS Code
2933990090
Applications
1. Pharmaceutical API: As a core API for the production of lipid-lowering drugs, Atorvastatin calcium (CAS: 134523-03-8) is widely used in the manufacture of oral tablets, capsules and other formulations for the treatment of hypercholesterolemia, familial hypercholesterolemia and other lipid metabolism disorders. 2. Pharmaceutical Intermediate:Atorvastatin calcium (CAS: 134523-03-8) can be used as an intermediate in the synthesis of modified atorvastatin derivatives to improve the solubility, bioavailability and efficacy of the drug. 3. Chemical R&D: Used in laboratory research and development, including the study of cholesterol metabolism mechanisms, the development of new statin drugs, and the optimization of synthesis processes related to Atorvastatin calcium (CAS: 134523-03-8) . 4. Fine Chemicals: Applied in the production of high-purity fine chemical products related to pharmaceutical and biochemical fields, providing raw material support for the fine chemical industry.
Purity
≥98%
Storage Conditions
Store in a cool, dry, well-ventilated area away from light and moisture
Appearance
White to off-white crystalline powder
Density
1.32 g/cm3
Melting Point
176-178 °C

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