2-Fluoro-4-iodonicotinaldehyde

2-Fluoro-4-iodonicotinaldehyde (CAS 153034-82-3) is a high-purity difunctional substituted fluorinated iodopyridine aldehyde fine chemical intermediate. This white to pale yellow crystalline solid possesses a stable pyridine heterocyclic skeleton, co-modified with fluoro, iodo and aldehyde active functional groups, featuring high chemical activity and reaction selectivity. The multi-substituted halogen structure effectively improves molecular stability and derivatization diversity, while the active aldehyde group supports oxidation, reduction and condensation reactions. With stable physical and chemical properties under low-temperature dry storage, 2-Fluoro-4-iodonicotinaldehyde (CAS 153034-82-3) is a core fluorinated pyridine building block widely used in pharmaceutical intermediate synthesis and precision organic synthesis.

1. Suzuki Cross-Coupling Reaction Synthesis: 2-Fluoro-4-iodonicotinaldehyde (CAS 153034-82-3) serves as a high-activity halogenated pyridine coupling reagent. The 4-position iodo group has excellent reaction activity, which can efficiently participate in palladium-catalyzed Suzuki cross-coupling reactions to construct multi-functional substituted fluoropyridine derivatives for high-precision fine organic synthesis. 2. Pharmaceutical Heterocyclic Intermediate Preparation: 2-Fluoro-4-iodonicotinaldehyde (CAS 153034-82-3) is a key synthetic intermediate for new drug R&D. The unique fluoro-iodo substituted pyridine aldehyde structure can optimize drug molecular lipophilicity and metabolic stability, widely applied in the synthesis of anti-tumor, antiviral and targeted small-molecule drug intermediates. 3. Fluorinated Functional Heterocyclic Derivatization: 2-Fluoro-4-iodonicotinaldehyde (CAS 153034-82-3) contains active aldehyde and halogen functional sites. It can undergo diversified structural modification reactions such as condensation and substitution, used for the preparation of high-value fluorinated nitrogen heterocyclic fine chemicals and biochemical functional materials. 4. Laboratory Synthetic Process Optimization: 2-Fluoro-4-iodonicotinaldehyde (CAS 153034-82-3) acts as a standard multi-halogenated pyridine aldehyde reagent. It is commonly used in laboratory organic synthesis mechanism research and new catalytic process development, providing stable raw material support for fluorinated heterocyclic compound route optimization.

≥98%

C6H3FINO

250.99

2 years under proper storage

White to pale yellow crystalline solid

Synthetic Grade, Pharmaceutical Intermediate Grade, Laboratory Grade

2.08±0.1 g/cm3

75-78°C