2-Fluoro-4-biphenylylboronic acid

2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2) is a high-purity fluorinated biphenyl boronic acid fine chemical. This compound has a stable biphenyl skeleton structure with fluoro substitution and active boronic acid functional groups, featuring moderate moisture sensitivity, excellent thermal stability and good solubility in conventional organic solvents such as methanol. The fluorinated biphenyl structure optimizes molecular steric hindrance and electronic properties, delivering high reaction selectivity in cross-coupling reactions. 2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2) is a core high-value organic synthesis building block, widely used in pharmaceutical intermediate customization, organic material synthesis and fine chemical derivatization.

1. Fluorinated Biphenyl Suzuki Cross-Coupling Synthesis:2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2) is a key monomer for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. Its unique fluorinated biphenyl structure effectively reduces side reactions and improves synthetic yield and product purity, serving as a critical raw material for preparing high-purity biphenyl derivative intermediates in fine chemical industrial production. 2. Pharmaceutical Intermediate Customized Manufacturing: 2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2) is an essential modular intermediate for new drug research and development. The fluorinated biphenyl functional structure can significantly enhance the lipophilicity and metabolic stability of drug molecules, and is widely applied in the customized synthesis of anti-inflammatory, analgesic and targeted therapeutic small-molecule pharmaceutical intermediates. 3. Functional Organic Material Preparation: 2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2) acts as a key precursor for high-performance organic functional materials. The stable biphenyl skeleton and active boronic acid groups support multi-step polymerization and structural modification reactions, which are used for the synthesis of organic optoelectronic materials, chemical sensing materials and polymer intermediates. 4. Laboratory Organic Synthesis Research: 2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2) is a standard high-purity laboratory synthetic reagent. With stable batch quality and unique fluorinated biphenyl reaction characteristics, it is widely used for organic reaction mechanism verification, synthetic route optimization and new compound development in scientific research projects.

99%

C12H10BFO2

216.02

2 years under proper storage

White to almost white powder or crystalline powder

Laboratory Grade, Industrial Grade, Pharmaceutical Grade

1.25±0.1 g/cm3

243-248°C

377.3±52.0°C at 760 mmHg