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H17B6 rabbit pAb

CAT: 0855-ES15851-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15851-01Size:50 µL
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Background
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013]
Description
The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. [provided by RefSeq, Aug 2013],
UniProt
O14756
Swiss Prot
O14756
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human H17B6 AA range: 28-78
Target
H17B6
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Microsome membrane ; Peripheral membrane protein ; Lumenal side . Early endosome membrane ; Peripheral membrane protein ; Lumenal side .
Gene ID (Human)
8630

UniProtKB · O14756

17-beta-hydroxysteroid dehydrogenase type 6

H17B6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14756
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HSD17B6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
17-beta-HSD 6, 17-beta-HSD6
EC number
1.1.1.105, 1.1.1.209, 1.1.1.239, 1.1.1.53, 1.1.1.62
Processing
Precursor
Secondary accessions
O43275
Protein keywords

Cellular component

Endoplasmic reticulumEndosomeMembraneMicrosome

PTM

Glycoprotein

Biological process

Lipid metabolismSteroid metabolism

Ligand

NAD

Molecular function

Oxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

Signal

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