Dolutegravir Intermediate-1

Dolutegravir Intermediate-1 (CAS: 1335210-23-5) is a high-purity pharmaceutical intermediate with the molecular formula C13H17NO8. It appears as white to off-white lyophilized powder under normal temperature and pressure. This compound is a key synthetic intermediate of Dolutegravir, a classic HIV integrase inhibitor drug. It features stable chemical structure, high synthesis activity and low impurity content, and is exclusively used in the pharmaceutical synthesis process of anti-HIV drugs.

Methyl 5-acetyl-1- (2,2-dimethoxyethyl) -3-methoxy-4-oxo-1,4-dihydropyridine-2-carboxylate, 1- (2,2-Dimethoxyethyl) -5-methoxy-6- (methoxycarbonyl) -4-oxo-1,4-dihydropyridine-3-carboxylic acid, Dolutegravir impurity 22

2933399090

1. Core Intermediate for Dolutegravir Synthesis Dolutegravir Intermediate-1 (CAS: 1335210-23-5) is a key raw material for the industrial synthesis of Dolutegravir. It participates in the core cyclization and modification reactions of the drug molecular structure, effectively improving the synthesis yield and product purity of finished Dolutegravir drugs, and is an indispensable intermediate in the mainstream synthetic route. 2. Anti-HIV Pharmaceutical R&D Research Dolutegravir Intermediate-1 (CAS: 1335210-23-5) is widely used in pharmaceutical laboratory research and new drug development. It can be used for synthetic process optimization, impurity profiling and pharmaceutical formulation research of HIV integrase inhibitor drugs, supporting the iterative upgrading of anti-viral drugs. 3. Pharmaceutical Impurity Reference Standard Dolutegravir Intermediate-1 (CAS: 1335210-23-5) can be used as a standard impurity reference substance for Dolutegravir finished drug testing. It supports HPLC detection, impurity content analysis and drug quality inspection in pharmaceutical factories, helping enterprises meet pharmaceutical production quality standards.

≥98%

C13H17NO8

315.28

2 years under proper storage

White to off-white lyophilized powder

Pharmaceutical Intermediate Grade

1.348 g/cm3 (Predicted)

Not available