Rocuronium (Bromide)

CAT: 0804-HY-17440-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-17440-01Size:5 mg
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Description
Rocuronium Bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation.
CAS Number
[119302-91-9]
Product Name Alternative
ORG 9426 (Bromide)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/rocuronium-bromide.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](C[C@H]([N+]3(CC=C)CCCC3)[C@@H]2OC(C)=O)([H])[C@]([C@]4([H])CC1)([H])CC[C@@]([C@]4(C)C5)([H])C[C@H](O)[C@H]5N6CCOCC6.[Br-]
Molecular Formula
C32H53BrN2O4
Molecular Weight
609.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Narimatsu E, Niiya T, Takahashi K, Pralidoxime inhibits paraoxon-induced depression of rocuronium-neuromuscular block in a time-dependentfashion. Am J Emerg Med. 2012 Jul;30 (6) :901-7.|[2]Wicks TC. The pharmacology of rocuronium bromide (ORG 9426) . AANA J. 1994 Feb;62 (1) :33-8.|[3]Wierda JM, Kleef UW, Lambalk LM, The pharmacodynamics and pharmacokinetics of Org 9426, a new non-depolarizing neuromuscular blocking agent, in patients anaesthetized with nitrous oxide, halothane and fentanyl. Can J Anaesth. 1991 May;38 (4 Pt 1) :430-5.|[4]Khuenl-Brady K, Castagnoli KP, Canfell PC, The neuromuscular blocking effects and pharmacokinetics of ORG 9426 and ORG 9616 in the cat. Anesthesiology. 1990 Apr;72 (4) :669-74.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Sci Rep. 2017 Apr 5;7:46098.|Hum Mol Genet. 2015 Aug 15;24 (16) :4648-59.

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CatalogName
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A10803-100Rocuronium bromide 100mg
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