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RPGF6 Polyclonal Antibody

CAT: 1027-RA34579-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA34579-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 cyclic nucleotide-binding domain., similarity:Contains 1 N-terminal Ras-GEF domain., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 Ras-associating domain., similarity:Contains 1 Ras-GEF domain., subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane., subunit:Interacts with the second PDZ domain of human PTP1e., tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas.
Gene ID
51735
Swiss Prot
Q8TEU7
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
176
Storage Conditions
-20°C/1 year
Protein Weight
176

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