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PABP4 Polyclonal Antibody

CAT: 1027-RA33960-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA33960-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Poly (A) binding protein cytoplasmic 4 (PABPC4) Homo sapiens Poly (A) -binding proteins (PABPs) bind to the poly (A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript va
Gene ID
8761
Swiss Prot
Q13310
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
70
Storage Conditions
-20°C/1 year
Protein Weight
70

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