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NSE2 Polyclonal Antibody

CAT: 1027-RA33645-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA33645-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair., pathway:Protein modification; protein sumoylation., PTM:Sumoylated, possibly via autosumoylation., similarity:Belongs to the NSE2 family., similarity:Contains 1 SP-RING-type zinc finger., subunit:Component of the SMC5-SMC6 complex which consists of SMC5, SMC6, NSMCE2/MMS21 and probably NSMCE1.
Gene ID
286053
Swiss Prot
Q96MF7
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
27
Storage Conditions
-20°C/1 year
Protein Weight
27

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