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NSE2 Polyclonal Antibody

CAT: 0965-JOT-AP12036-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12036-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.,pathway:Protein modification; protein sumoylation.,PTM:Sumoylated, possibly via autosumoylation.,Belongs to the NSE2 family.,Contains 1 SP-RING-type zinc finger.,subunit:Component of the SMC5-SMC6 complex which consists of SMC5, SMC6, NSMCE2/MMS21 and probably NSMCE1.,
CAS Number
9007-83-4
Synonyms
E3 SUMO-protein ligase NSE2 ;EC 6.3.2.-;MMS21 homolog;hMMS21;Non-structural maintenance of chromosomes element 2 homolog;Non-SMC element 2 homolog
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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