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KPNA6 rabbit pAb

CAT: 1027-RA32996-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA32996-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
Product Name Alternative
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene ID
23633
Swiss Prot
O60684
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IP
Dilution
IP: 2-10µg/mL WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.07% sodium azide.
Molecular Weight
60
Storage Conditions
-20°C/1 year
Protein Weight
60

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