BEX3 Polyclonal Antibody

• Background:

  Domain:The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR., function:May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity) . May play an important role in the pathogenesis of neurogenetic diseases., miscellaneous:Binds transition metals., PTM:Ubiquitinated. Degraded by the proteasome., similarity:Belongs to the BEX family., subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria., subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE) . Interacts with DIABLO/SMAC (By similarity) . Binds to the DEATH domain of p75NTR/NGFR., tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.

• Gene ID:

  27018

• Swiss Prot:

  Q00994

• Cross Reactivity:

  Human; Rat; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight:

  12

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  12