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BEX3 Polyclonal Antibody

CAT: 0965-JOT-AP14453-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14453-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.,May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.,miscellaneous:Binds transition metals.,PTM:Ubiquitinated. Degraded by the proteasome.,Belongs to the BEX family.,subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.,subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC (By similarity). Binds to the DEATH domain of p75NTR/NGFR.,tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.,
CAS Number
9007-83-4
Synonyms
Protein BEX3 ;Brain-expressed X-linked protein 3;Nerve growth factor receptor-associated protein 1;Ovarian granulosa cell 13.0 kDa protein HGR74;p75NTR-associated cell death executor
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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