STAT2 Polyclonal Antibody

• Background:

  Signal transducer and activator of transcription 2 (STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

• Product Name Alternative:

  STAT2; Signal transducer and activator of transcription 2; p113

• Gene ID:

  6773

• Swiss Prot:

  P52630

• Cross Reactivity:

  Human

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Dilution:

  Western Blot: 1/500 - 1/2000

• Buffer:

  PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• Molecular Weight:

  98

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  98