SR-2A Polyclonal Antibody

• Background:

  5-hydroxytryptamine receptor 2A (HTR2A) Homo sapiens This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD) . MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

• Product Name Alternative:

  HTR2A; HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A

• Gene ID:

  3356

• Swiss Prot:

  P28223

• Cross Reactivity:

  Human; Rat; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC-p; IF/ICC; ELISA

• Dilution:

  Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Storage Conditions:

  -20°C/1 year