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SIK1 Polyclonal Antibody

CAT: 1027-RA29829-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA29829-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by phosphorylation on Thr-182 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39., function:Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 UBA domain., subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ., subunit:Binds to and is activated by YWHAZ when phosphorylated on Thr-182.
Product Name Alternative
SIK1; SIK; SNF1LK; Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK
Gene ID
150094
Swiss Prot
P57059
Cross Reactivity
Human; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
85
Storage Conditions
-20°C/1 year
Protein Weight
85

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