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Perforin 1 Polyclonal Antibody

CAT: 1027-RA28680-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA28680-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Perforin 1 (PRF1) Homo sapiens The protein encoded by this gene has structural and functional similarities to complement component 9 (C9) . Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Product Name Alternative
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Gene ID
5551
Swiss Prot
P14222
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; ELISA
Dilution
WB 1:500-2000, IHC 1:50-200, ELISA 1:10000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
61
Storage Conditions
-20°C/1 year
Protein Weight
61