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KOR-1 Polyclonal Antibody

CAT: 1027-RA26700-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA26700-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Product Name Alternative
OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Cross Reactivity
Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; WB; ELISA
Dilution
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
42
Storage Conditions
-20°C/1 year
Protein Weight
42

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