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Defensin α4 Polyclonal Antibody

CAT: 1027-RA24166-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA24166-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Defensin alpha 4 (DEFA4) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
Product Name Alternative
DEFA4; DEF4; Neutrophil defensin 4; Defensin; alpha 4; HNP-4; HP-4
Gene ID
1669
Swiss Prot
P12838
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year